內(nèi)質(zhì)網(wǎng)定位蛋白ERGI3抗體產(chǎn)品應(yīng)用

中文名稱(chēng)    內(nèi)質(zhì)網(wǎng)定位蛋白ERGI3抗體    

英文名稱(chēng)    ERGI3    

別    名    2310015B14Rik; AV318804; C20orf47; CGI 54; D2Ucla1; dJ477O4.2; DKFZp547A2190; Endoplasmic reticulum Golgi intermediate compartment protein 3; endoplasmic reticulum localized protein ERp43; Endoplasmic reticulum-Golgi intermediate compartment protein 3; ERGI3_HUMAN; ERGIC and golgi 3; ergic3; ERV46; NY BR 84; PRO0989; RP23-220D12.2; RP3-477O4.1; SDBCAG84; serologically defined breast cancer antigen 84; Serologically defined breast cancer antigen NY BR 84; Serologically defined breast cancer antigen NY-BR-84.    

供 應(yīng) 商    遠(yuǎn)慕生物    

研究領(lǐng)域    細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)運(yùn)蛋白      

抗體來(lái)源    Rabbit    

克隆類(lèi)型    Polyclonal    

交叉反應(yīng)    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,     

產(chǎn)品應(yīng)用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 內(nèi)質(zhì)網(wǎng)定位蛋白ERGI3抗體（石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    43kDa    

細(xì)胞定位    細(xì)胞漿 細(xì)胞膜     

性    狀    Lyophilized or Liquid    

濃    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human ERGI3/ERGIC-3    

亞    型    IgG    

純化方法    affinity purified by Protein A    

儲(chǔ) 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存條件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

內(nèi)質(zhì)網(wǎng)定位蛋白ERGI3抗體產(chǎn)品介紹    background:

Cycling proteins play important roles in the organization and function of the early secretory pathway by participating in membrane traffic and selective transport of cargo between the endoplasmic reticulum (ER), the intermediate compartment (ERGIC), and the Golgi. A family of membrane bound, ubiquitous proteins involved in the selective transport of newly synthesized glycoproteins from the ER to the ERGIC include VIP36, ERGIC-53, ERGIC-1, ERGIC-2 and ERGIC-3. ERGIC-1, also designated ERGIC32, is thought to modulate the activity of a complex formed by ERGIC-2, also designated Erv41, and ERGIC-3, also designated Erv46. ERGIC-2 and ERGIC-3 are both mammalian homologs of yeast proteins abundant in COPII-coated vesicles and localize to the Cis-face of the Golgi apparatus.

Function:
Possible role in transport between endoplasmic reticulum and Golgi.

Subunit:
Interacts with ERGIC1/ERGIC32.

Subcellular Location:
Endoplasmic reticulum-Golgi intermediate compartment membrane. Golgi apparatus > cis-Golgi network membrane. Endoplasmic reticulum membrane. Cycles between the endoplasmic reticulum and the Golgi.

Similarity:
Belongs to the ERGIC family.

Database links:

Entrez Gene: 51614 Human

Entrez Gene: 66366 Mouse

Entrez Gene: 296306 Rat

SwissProt: Q9Y282 Human

SwissProt: Q9CQE7 Mouse

Unigene: 472558 Human

Unigene: 141276 Mouse


Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.