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產(chǎn)品名稱:

泊馬度胺

 
產(chǎn)品編號(hào): AS-0259 
別名: 泊馬度胺;3-氨基-N-(2,6-二氧代-3-哌啶基)鄰苯二甲酰亞胺;3-(七氟異丙氧基)丙基三氯硅烷;4-氨基-2-(2,6-二氧代哌啶-3-基)異吲哚-1,3-二酮;Pomalidomide 泊馬度胺;Pomalidomide 抑制劑;泊利度胺;3-氨基-N-(2,6-二氧-3-哌啶基)苯鄰二甲酰亞胺;TNF-alpha抑制劑;泊馬度胺-D4;泊馬度胺, 一種TNF-Α抑制劑;4-氨基-2-(2,6-二氧哌啶-3-基)異吲哚啉-1,3-二酮;泊馬度胺雜質(zhì) 
英文名: pomalidomide 
CAS號(hào): 19171-19-8
分子式: C13H11N3O4 
分子量: 273.24 
泊馬度胺
Pomalidomide, also known as CC4047, is an orally bioavailable derivative of thalidomide with potential immunomodulating, antiangiogenic and antineoplastic activities. Although its exact mechanism of action has yet to be fully elucidated, pomalidomide appears to inhibit TNF-alpha production, enhance the activity of T cells and natural killer (NK) cells and enhance antibody-dependent cellular cytotoxicity (ADCC). Pomalidomide was approved on February 8, 2013 as a treatment for relapsed and refractory multiple myeloma.
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